hrp0082p3-d3-659 | Autoimmune Endocrine Disease | ESPE2014

Evaluation of the Relation between Thyroid Dysfunction and Oxidant/Antioxidant Status in Obese Children

Asci Ali , Bulus Derya , Andiran Nesibe , Kocer-Gumusel Belma

Background: Obesity has been defined as ‘abnormal or excessive fat accumulation that may impair health’ by World Health Organization.Objective and hypotheses: Although the role of oxidative stress in obesity has been interest of subject in recent studies, comprehensive studies evaluating parameters of oxidant/antioxidant status in children are limited. Moreover, there has been an increasing focus on the relationship between obesity and thyroid ...

hrp0082p2-d1-537 | Puberty and Neuroendocrinology | ESPE2014

The Evaluation of Possible Role of Endocrine Disrupters in Precocious Puberty

Bulus Derya , Asci Ali , Andiran Nesibe , Kocer-Gumusel Belma , Colakoglu Elif Yagli

Background: Human health might be negatively affected by chemicals named as endocrine disrupters. Researchers showed that phthalates (bis-(2-ethylhexyl) phthalate (DEHP), mono-(2-ethylhexyl) phthalate (MEHP)) and bisphenol A (BPA) have an anti-androgenic and/or estrogenic effects. These endocrine disruptors are accused in occurrence and/or possible increase in unusual early puberty in girls in recent years.Objective and hypotheses: The aim of th...